2QIC
Crystal Structure of the ING1 PHD Finger in complex with a Histone H3K4ME3 peptide
Summary for 2QIC
Entry DOI | 10.2210/pdb2qic/pdb |
Descriptor | Inhibitor of growth protein 1, H3K4ME3 PEPTIDE, ZINC ION, ... (4 entities in total) |
Functional Keywords | phd, ing1, histone, h3k4me3, chromatin, antitumor protein, apoptosis |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus (Probable): Q9UK53 |
Total number of polymer chains | 2 |
Total formula weight | 8557.31 |
Authors | Pena, P.V.,Champagne, K.,Zhao, R.,Kutateladze, T.G. (deposition date: 2007-07-03, release date: 2008-05-13, Last modification date: 2023-08-30) |
Primary citation | Pena, P.V.,Hom, R.A.,Hung, T.,Lin, H.,Kuo, A.J.,Wong, R.P.,Subach, O.M.,Champagne, K.S.,Zhao, R.,Verkhusha, V.V.,Li, G.,Gozani, O.,Kutateladze, T.G. Histone H3K4me3 binding is required for the DNA repair and apoptotic activities of ING1 tumor suppressor. J.Mol.Biol., 380:303-312, 2008 Cited by PubMed: 18533182DOI: 10.1016/j.jmb.2008.04.061 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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