2QFW
Crystal structure of Saccharomyces cerevesiae mitochondrial NADP(+)-dependent isocitrate dehydrogenase in complex with isocitrate
Summary for 2QFW
Entry DOI | 10.2210/pdb2qfw/pdb |
Related | 2QFV 2QFX 2QFY |
Descriptor | Isocitrate dehydrogenase [NADP], ISOCITRIC ACID (3 entities in total) |
Functional Keywords | rossmann fold, oxidoreductase |
Biological source | Saccharomyces cerevisiae (yeast) |
Cellular location | Mitochondrion: P21954 |
Total number of polymer chains | 6 |
Total formula weight | 290011.26 |
Authors | Peng, Y.J.,Ding, J.P. (deposition date: 2007-06-28, release date: 2008-07-01, Last modification date: 2023-10-25) |
Primary citation | Peng, Y.J.,Zhong, C.,Huang, W.,Ding, J.P. Structural studies of Saccharomyces cerevesiae mitochondrial NADP-dependent isocitrate dehydrogenase in different enzymatic states reveal substantial conformational changes during the catalytic reaction Protein Sci., 17:1542-1554, 2008 Cited by PubMed: 18552125DOI: 10.1110/ps.035675.108 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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