2QFB
Crystal structure of the regulatory domain of human RIG-I with bound Zn
Summary for 2QFB
Entry DOI | 10.2210/pdb2qfb/pdb |
Related | 2QFD |
Descriptor | Probable ATP-dependent RNA helicase DDX58, ZINC ION (3 entities in total) |
Functional Keywords | zinc finger, alternative splicing, antiviral defense, atp-binding, helicase, hydrolase, immune response, innate immunity, interferon induction, nucleotide-binding, polymorphism, rna-binding, ubl conjugation |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: O95786 |
Total number of polymer chains | 10 |
Total formula weight | 169189.07 |
Authors | Cui, S.,Lammens, A.,Lammens, K.,Hopfner, K.P. (deposition date: 2007-06-27, release date: 2008-02-12, Last modification date: 2023-08-30) |
Primary citation | Cui, S.,Eisenacher, K.,Kirchhofer, A.,Brzozka, K.,Lammens, A.,Lammens, K.,Fujita, T.,Conzelmann, K.K.,Krug, A.,Hopfner, K.P. The C-Terminal Regulatory Domain Is the RNA 5'-Triphosphate Sensor of RIG-I. Mol.Cell, 29:169-179, 2008 Cited by PubMed: 18243112DOI: 10.1016/j.molcel.2007.10.032 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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