2Q98
X-ray structure of a prolactin antagonist
Summary for 2Q98
Entry DOI | 10.2210/pdb2q98/pdb |
Descriptor | Prolactin (2 entities in total) |
Functional Keywords | antagonist receptor interaction, hormone |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P01236 |
Total number of polymer chains | 1 |
Total formula weight | 22364.52 |
Authors | Broutin, I.J.L.,Ducruix, A.,Jomain, J.B.,Goffin, V. (deposition date: 2007-06-12, release date: 2007-09-11, Last modification date: 2023-08-30) |
Primary citation | Jomain, J.B.,Tallet, E.,Broutin, I.,Hoos, S.,van Agthoven, J.,Ducruix, A.,Kelly, P.A.,Kragelund, B.B.,England, P.,Goffin, V. Structural and thermodynamic bases for the design of pure prolactin receptor antagonists: X-ray structure of Del1-9-G129R-hPRL. J.Biol.Chem., 282:33118-33131, 2007 Cited by PubMed: 17785459DOI: 10.1074/jbc.M704364200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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