2Q80

Crystal structure of human geranylgeranyl pyrophosphate synthase bound to GGPP

「2FVI」から置き換えられました

2Q80 の概要

• エントリーDOI: 10.2210/pdb2q80/pdb
• 分子名称: Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION, GERANYLGERANYL DIPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: isoprenoid pathway, isopentenyl transferase, structural genomics, structural genomics consortium, sgc, transferase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: O95749
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 213011.78

構造登録者

Kavanagh, K.L.,Dunford, J.E.,Bunkoczi, G.,Smee, C.,von Delft, F.,Arrowsmith, C.,Weigelt, J.,Edwards, A.,Sundstrom, M.,Oppermann, U.,Structural Genomics Consortium (SGC) (登録日: 2007-06-08, 公開日: 2007-06-19, 最終更新日: 2024-04-03)

• 主引用文献: Kavanagh, K.L.,Dunford, J.E.,Bunkoczi, G.,Russell, R.G.,Oppermann, U.; The crystal structure of human geranylgeranyl pyrophosphate synthase reveals a novel hexameric arrangement and inhibitory product binding; J.Biol.Chem., 281:22004-22012, 2006; PubMed: 16698791; DOI: 10.1074/jbc.M602603200

実験手法

X-RAY DIFFRACTION (2.7 Å)