2Q7N

Crystal structure of Leukemia inhibitory factor in complex with LIF receptor (domains 1-5)

2Q7N の概要

• エントリーDOI: 10.2210/pdb2q7n/pdb
• 関連するPDBエントリー: 1PVH
• 分子名称: Leukemia inhibitory factor receptor, Leukemia inhibitory factor, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: cytokine cell surface receptor complex lifr lif, cytokine receptor-cytokine complex, cytokine receptor/cytokine
• 由来する生物種: Mus musculus (house mouse); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 158379.13

構造登録者

Huyton, T.,Zhang, J.G.,Nicola, N.A.,Garrett, T.P.J. (登録日: 2007-06-07, 公開日: 2007-07-31, 最終更新日: 2023-08-30)

• 主引用文献: Huyton, T.,Zhang, J.G.,Luo, C.S.,Lou, M.Z.,Hilton, D.J.,Nicola, N.A.,Garrett, T.P.; An unusual cytokine:Ig-domain interaction revealed in the crystal structure of leukemia inhibitory factor (LIF) in complex with the LIF receptor.; Proc.Natl.Acad.Sci.USA, 104:12737-12742, 2007; PubMed: 17652170; DOI: 10.1073/pnas.0705577104

実験手法

X-RAY DIFFRACTION (4 Å)