2Q5Q
X-ray structure of phenylpyruvate decarboxylase in complex with 3-deaza-ThDP and 5-phenyl-2-oxo-valeric acid
Summary for 2Q5Q
Entry DOI | 10.2210/pdb2q5q/pdb |
Related | 2Q5J 2Q5L 2Q5O 2nxw |
Descriptor | Phenylpyruvate decarboxylase, MAGNESIUM ION, 2-{4-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-3-METHYLTHIOPHEN-2-YL}ETHYL TRIHYDROGEN DIPHOSPHATE, ... (7 entities in total) |
Functional Keywords | thiamine diphosphate, symmetrical dimer of dimers, closed active site loops, substrate complex, lyase |
Biological source | Azospirillum brasilense |
Total number of polymer chains | 2 |
Total formula weight | 122652.07 |
Authors | Versees, W.,Spaepen, S.,Wood, M.D.,Leeper, F.J.,Vanderleyden, J.,Steyaert, J. (deposition date: 2007-06-01, release date: 2007-10-23, Last modification date: 2023-08-30) |
Primary citation | Versees, W.,Spaepen, S.,Wood, M.D.,Leeper, F.J.,Vanderleyden, J.,Steyaert, J. Molecular mechanism of allosteric substrate activation in a thiamine diphosphate-dependent decarboxylase. J.Biol.Chem., 282:35269-35278, 2007 Cited by PubMed: 17905741DOI: 10.1074/jbc.M706048200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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