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2Q58

Cryptosporidium parvum putative polyprenyl pyrophosphate synthase (cgd4_2550) in complex with zoledronate

Replaces:  2HER
Summary for 2Q58
Entry DOI10.2210/pdb2q58/pdb
DescriptorFarnesyl pyrophosphate synthase, MAGNESIUM ION, ZOLEDRONIC ACID, ... (4 entities in total)
Functional Keywordsfarnesyl diphosphate synthase, structural genomics, structural genomics consortium, sgc, transferase
Biological sourceCryptosporidium parvum
Total number of polymer chains2
Total formula weight86636.11
Authors
Primary citationArtz, J.D.,Dunford, J.E.,Arrowood, M.J.,Dong, A.,Chruszcz, M.,Kavanagh, K.L.,Minor, W.,Russell, R.G.,Ebetino, F.H.,Oppermann, U.,Hui, R.
Targeting a uniquely nonspecific prenyl synthase with bisphosphonates to combat cryptosporidiosis
Chem.Biol., 15:1296-, 2008
Cited by
PubMed: 19101474
DOI: 10.1016/j.chembiol.2008.10.017
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.37 Å)
Structure validation

217705

건을2024-03-27부터공개중

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