2Q3I

Crystal structure of the D10-P3/IQN17 complex: a D-peptide inhibitor of HIV-1 entry bound to the GP41 coiled-coil pocket

2Q3I の概要

• エントリーDOI: 10.2210/pdb2q3i/pdb
• 関連するPDBエントリー: 1CZQ
• 分子名称: Fusion protein between the Coiled-Coil pocket of HIV GP41 and gcn4-PIQI, D-peptide, CHLORIDE ION, ... (4 entities in total)
• 機能のキーワード: envelope glycoprotein, viral protein-inhibitor complex, viral protein/inhibitor
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 7271.01

構造登録者

Malashkevich, V.N.,Eckert, D.M.,Hong, L.H.,Carr, P.A.,Kim, P.S. (登録日: 2007-05-30, 公開日: 2007-06-12, 最終更新日: 2023-11-15)

• 主引用文献: Eckert, D.M.,Malashkevich, V.N.,Hong, L.H.,Carr, P.A.,Kim, P.S.; Inhibiting HIV Entry: Discovery of D-Peptide Inhibitors that Target the Gp41 Coiled-Coil Pocket; Cell(Cambridge,Mass.), 99:103-105, 1999; PubMed: 10520998; DOI: 10.1016/S0092-8674(00)80066-5

実験手法

X-RAY DIFFRACTION (1.5 Å)