2Q1B

Carbonic Anhydrase II in Complex with Saccharin

Summary for 2Q1B

• Entry DOI: 10.2210/pdb2q1b/pdb
• Related: 1oq5 1z9y
• Descriptor: Carbonic anhydrase 2, ZINC ION, MERCURY (II) ION, ... (6 entities in total)
• Functional Keywords: 10-stranded, twisted beta-sheet, lyase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P00918
• Total number of polymer chains: 1
• Total formula weight: 29925.78

Authors

Klebe, G.,Heine, A.,Koehler, K. (deposition date: 2007-05-24, release date: 2007-09-04, Last modification date: 2023-08-30)

• Primary citation: Kohler, K.,Hillebrecht, A.,Schulze Wischeler, J.,Innocenti, A.,Heine, A.,Supuran, C.T.,Klebe, G.; Saccharin Inhibits Carbonic Anhydrases: Possible Explanation for its Unpleasant Metallic Aftertaste.; Angew.Chem.Int.Ed.Engl., 46:7697-7699, 2007; PubMed: 17705204; DOI: 10.1002/anie.200701189

Experimental method

X-RAY DIFFRACTION (1.7 Å)