2PZI

Crystal Structure of Protein kinase PknG from Mycobacterium tuberculosis in Complex with Tetrahydrobenzothiophene AX20017

Summary for 2PZI

Entry DOI	10.2210/pdb2pzi/pdb
Related	1ATP 1O6Y 2FUM
Descriptor	Probable serine/threonine-protein kinase pknG, CHLORIDE ION, CADMIUM ION, ... (6 entities in total)
Functional Keywords	serine/threonine-protein kinase, atp-recognition, kinase-inhibitor complex, rubredoxin fold, tpr domain, transferase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	2
Total formula weight	149707.49
Authors	Honnappa, S.,Steinmetz, M.O. (deposition date: 2007-05-18, release date: 2007-07-24, Last modification date: 2024-02-21)
Primary citation	Scherr, N.,Honnappa, S.,Kunz, G.,Mueller, P.,Jayachandran, R.,Winkler, F.,Pieters, J.,Steinmetz, M.O. Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. Proc.Natl.Acad.Sci.Usa, 104:12151-12156, 2007 Cited by PubMed: 17616581 DOI: 10.1073/pnas.0702842104 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation