2PZF

Minimal human CFTR first nucleotide binding domain as a head-to-tail dimer with delta F508

2PZF の概要

関連するPDBエントリー1XMI 1XMJ 2BB0 2BBS 2BBT 1R0Z 1R10 2IXE 1L2T 1Q12 1XEF 2HYD 2PZE 2PZG
分子名称Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
機能のキーワードnbd, abc transporter, cftr, f508, hydrolase
由来する生物種Homo sapiens (Human)
ポリマー鎖数2
分子量合計51819.44
構造登録者
主引用文献
Atwell, S.,Brouillette, C.G.,Conners, K.,Emtage, S.,Gheyi, T.,Guggino, W.B.,Hendle, J.,Hunt, J.F.,Lewis, H.A.,Lu, F.,Protasevich, I.I.,Rodgers, L.A.,Romero, R.,Wasserman, S.R.,Weber, P.C.,Wetmore, D.,Zhang, F.F.,Zhao, X.
Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant.
Protein Eng.Des.Sel., 23:375-384, 2010
PubMed: 20150177 (主引用文献が同じPDBエントリー)
DOI: 10.1093/protein/gzq004
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2 Å)
NMR情報
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構造検証レポート

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers20 0.9% 8.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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