2PYE
Crystal Structures of High Affinity Human T-Cell Receptors Bound to pMHC RevealNative Diagonal Binding Geometry TCR Clone C5C1 Complexed with MHC
Summary for 2PYE
Entry DOI | 10.2210/pdb2pye/pdb |
Related | 2BNR 2F53 2F54 2P5E 2P5W |
Descriptor | HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Cancer/testis antigen 1B, ... (10 entities in total) |
Functional Keywords | t-cell receptor, cdr3, phage display, mutant, high affinity, ny-eso-1, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P01892 Secreted: P61769 Cytoplasm: P78358 |
Total number of polymer chains | 5 |
Total formula weight | 96013.35 |
Authors | Sami, M.,Rizkallah, P.J.,Dunn, S.,Li, Y.,Moysey, R.,Vuidepot, A.,Baston, E.,Todorov, P.,Molloy, P.,Gao, F.,Boulter, J.M.,Jakobsen, B.K. (deposition date: 2007-05-16, release date: 2007-09-25, Last modification date: 2023-12-27) |
Primary citation | Sami, M.,Rizkallah, P.J.,Dunn, S.,Molloy, P.,Moysey, R.,Vuidepot, A.,Baston, E.,Todorov, P.,Yi, L.,Gao, F.,Boulter, J.M.,Jakobsen, B.K. Crystal structures of high affinity human T-cell receptors bound to peptide major histocompatibility complex reveal native diagonal binding geometry Protein Eng.Des.Sel., 20:397-403, 2007 Cited by PubMed: 17644531DOI: 10.1093/protein/gzm033 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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