2PXJ

The complex structure of JMJD2A and monomethylated H3K36 peptide

Summary for 2PXJ

Entry DOI	10.2210/pdb2pxj/pdb
Related	2GP3 2GP5 2P5B
Descriptor	JmjC domain-containing histone demethylation protein 3A, monomethylated Histone H3K36 peptide, ZINC ION, ... (6 entities in total)
Functional Keywords	jmjd2a; histone demethylase; jmjc; h3k36, oxidoreductase
Biological source	Homo sapiens (human) More
Cellular location	Nucleus: O75164
Total number of polymer chains	4
Total formula weight	86106.34
Authors	Chen, Z.,Zang, J.,Kappler, J.,Hong, X.,Crawford, F.,Zhang, G. (deposition date: 2007-05-14, release date: 2007-06-12, Last modification date: 2023-08-30)
Primary citation	Chen, Z.,Zang, J.,Kappler, J.,Hong, X.,Crawford, F.,Wang, Q.,Lan, F.,Jiang, C.,Whetstine, J.,Dai, S.,Hansen, K.,Shi, Y.,Zhang, G. Structural basis of the recognition of a methylated histone tail by JMJD2A Proc.Natl.Acad.Sci.Usa, 104:10818-10823, 2007 Cited by PubMed: 17567753 DOI: 10.1073/pnas.0704525104 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation