2PW2

Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 in complex with gp41 Peptide ELDKWKSL

Summary for 2PW2

Entry DOI	10.2210/pdb2pw2/pdb
Related	2P8L 2P8M 2P8P 2PR4 2PW1
Descriptor	2F5 Fab' heavy chain, 2F5 Fab' light chain, peptide epitope, ... (4 entities in total)
Functional Keywords	hiv-1, gp41, 2f5, neutralizing antibody, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	49369.46
Authors	Bryson, S.,Julien, J.-P.,Hynes, R.C.,Pai, E.F. (deposition date: 2007-05-10, release date: 2007-05-22, Last modification date: 2011-07-13)
Primary citation	Bryson, S.,Julien, J.P.,Hynes, R.C.,Pai, E.F. Crystallographic definition of the epitope promiscuity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5: vaccine design implications. J.Virol., 83:11862-11875, 2009 Cited by PubMed: 19740978 DOI: 10.1128/JVI.01604-09 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.55 Å)

Structure validation