2PW1
Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 in complex with gp41 Peptide ELDKWNSL
Summary for 2PW1
Entry DOI | 10.2210/pdb2pw1/pdb |
Related | 2P8L 2P8M 2P8P 2PR4 2PW2 |
Descriptor | 2F5 Fab fragment heavy chain, 2F5 Fab fragment light chain, peptide epitope, ... (4 entities in total) |
Functional Keywords | hiv-1, 2f5, gp41, neutralizing antibody, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 49354.38 |
Authors | Bryson, S.,Julien, J.-P.,Hynes, R.C.,Pai, E.F. (deposition date: 2007-05-10, release date: 2007-05-22, Last modification date: 2011-07-13) |
Primary citation | Bryson, S.,Julien, J.P.,Hynes, R.C.,Pai, E.F. Crystallographic definition of the epitope promiscuity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5: vaccine design implications. J.Virol., 83:11862-11875, 2009 Cited by PubMed: 19740978DOI: 10.1128/JVI.01604-09 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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