2PVR

Crystal structure of the catalytic subunit of protein kinase CK2 (C-terminal deletion mutant 1-335) in complex with two sulfate ions

2PVR の概要

• エントリーDOI: 10.2210/pdb2pvr/pdb
• 関連するPDBエントリー: 1DAY 1JWH 1LP4 1LPU 1PJK 1YMI
• 分子名称: Casein kinase II subunit alpha, catalytic subunit, SULFATE ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (4 entities in total)
• 機能のキーワード: eukaryotic protein kinase fold, cmgc kinases, signaling protein, transferase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus : P68400
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 40633.87

構造登録者

Niefind, K.,Yde, C.W.,Ermakova, I.,Issinger, O.-G. (登録日: 2007-05-10, 公開日: 2007-06-26, 最終更新日: 2023-08-30)

• 主引用文献: Niefind, K.,Yde, C.W.,Ermakova, I.,Issinger, O.G.; Evolved to Be Active: Sulfate Ions Define Substrate Recognition Sites of CK2alpha and Emphasise its Exceptional Role within the CMGC Family of Eukaryotic Protein Kinases; J.Mol.Biol., 370:427-438, 2007; PubMed: 17524418; DOI: 10.1016/j.jmb.2007.04.068

実験手法

X-RAY DIFFRACTION (1.605 Å)