2PUQ
Crystal structure of active site inhibited coagulation factor VIIA in complex with soluble tissue factor
Replaces: 2PMMSummary for 2PUQ
Entry DOI | 10.2210/pdb2puq/pdb |
Related PRD ID | PRD_000285 |
Descriptor | Coagulation factor VII, Tissue factor, TRP-TYR-THR-ARG CHLOROMETHYLKETONE INHIBITOR, ... (8 entities in total) |
Functional Keywords | active site inhibitor, blood clotting, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 62576.05 |
Authors | Bjelke, J.R.,Rasmussen, H.B. (deposition date: 2007-05-09, release date: 2007-05-22, Last modification date: 2023-08-30) |
Primary citation | Larsen, K.S.,Ostergaard, H.,Bjelke, J.R.,Olsen, O.H.,Rasmussen, H.B.,Christensen, L.,Kragelund, B.B.,Stennicke, H.R. Engineering the substrate and inhibitor specificities of human coagulation Factor VIIa Biochem.J., 405:429-438, 2007 Cited by PubMed: 17456045DOI: 10.1042/BJ20061901 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
Download full validation report