2PUF
CRYSTAL STRUCTURE OF THE LACI FAMILY MEMBER, PURR, BOUND TO DNA: MINOR GROOVE BINDING BY ALPHA HELICES
Summary for 2PUF
Entry DOI | 10.2210/pdb2puf/pdb |
Descriptor | DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), PROTEIN (PURINE REPRESSOR), GUANINE, ... (4 entities in total) |
Functional Keywords | complex (dna-binding protein-dna), dna-binding regulatory protein, extended corepressor specificity, transcription-dna complex, transcription/dna |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 43416.04 |
Authors | Lu, F.,Schumacher, M.A.,Arvidson, D.N.,Haldimann, A.,Wanner, B.L.,Zalkin, H.,Brennan, R.G. (deposition date: 1997-10-04, release date: 1998-05-06, Last modification date: 2024-02-21) |
Primary citation | Lu, F.,Schumacher, M.A.,Arvidson, D.N.,Haldimann, A.,Wanner, B.L.,Zalkin, H.,Brennan, R.G. Structure-based redesign of corepressor specificity of the Escherichia coli purine repressor by substitution of residue 190. Biochemistry, 37:971-982, 1998 Cited by PubMed: 9454587DOI: 10.1021/bi971942s PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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