2PTR

Crystal structure of Escherichia coli adenylosuccinate lyase mutant H171A with bound adenylosuccinate substrate

Summary for 2PTR

• Entry DOI: 10.2210/pdb2ptr/pdb
• Related: 2PTQ 2PTS
• Descriptor: Adenylosuccinate lyase, 2-[9-(3,4-DIHYDROXY-5-PHOSPHONOOXYMETHYL-TETRAHYDRO-FURAN-2-YL)-9H-PURIN-6-YLAMINO]-SUCCINIC ACID (3 entities in total)
• Functional Keywords: adenylosuccinate lyase, mutant-substrate complex, lyase
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 105665.44

Authors

Tsai, M.,Howell, P.L. (deposition date: 2007-05-08, release date: 2007-07-03, Last modification date: 2024-04-03)

• Primary citation: Tsai, M.,Koo, J.,Yip, P.,Colman, R.F.,Segall, M.L.,Howell, P.L.; Substrate and Product Complexes of Escherichia coli Adenylosuccinate Lyase Provide New Insights into the Enzymatic Mechanism.; J.Mol.Biol., 370:541-554, 2007; PubMed: 17531264; DOI: 10.1016/j.jmb.2007.04.052

Experimental method

X-RAY DIFFRACTION (1.85 Å)