2PR4
Crystal Structure of Fab' from the HIV-1 Neutralizing Antibody 2F5
Summary for 2PR4
Entry DOI | 10.2210/pdb2pr4/pdb |
Related | 2P8L 2P8M 2P8P |
Descriptor | nmAb 2F5 Fab' Heavy Chain, nmAb 2F5 Fab' light Chain (3 entities in total) |
Functional Keywords | nmab 2f5, gp41, hiv, viral protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 48365.28 |
Authors | Bryson, S.,Julien, J.-P.,Pai, E.F. (deposition date: 2007-05-03, release date: 2007-05-15, Last modification date: 2011-07-13) |
Primary citation | Julien, J.P.,Bryson, S.,Nieva, J.L.,Pai, E.F. Structural details of HIV-1 recognition by the broadly neutralizing monoclonal antibody 2F5: epitope conformation, antigen-recognition loop mobility, and anion-binding site. J.Mol.Biol., 384:377-392, 2008 Cited by PubMed: 18824005DOI: 10.1016/j.jmb.2008.09.024 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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