2PQF

Human Poly(ADP-Ribose) Polymerase 12, Catalytic fragment in complex with an inhibitor 3-Aminobenzoic acid

Summary for 2PQF

Entry DOI	10.2210/pdb2pqf/pdb
Descriptor	Poly [ADP-ribose] polymerase 12, 3-AMINOBENZOIC ACID, CITRIC ACID, ... (4 entities in total)
Functional Keywords	enzyme-inhibitor complex, catalytic fragment, structural genomics, structural genomics consortium, sgc, transferase
Biological source	Homo sapiens (human)
Cellular location	Nucleus : Q9H0J9
Total number of polymer chains	6
Total formula weight	138919.48
Authors	Karlberg, T.,Lehtio, L.,Arrowsmith, C.H.,Berglund, H.,Busam, R.D.,Collins, R.,Dahlgren, L.G.,Edwards, A.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Hogbom, M.,Johansson, I.,Kallas, A.,Kotenyova, T.,Moche, M.,Nordlund, P.,Nyman, T.,Persson, C.,Sagemark, J.,Sundstrom, M.,Thorsell, A.G.,Van Den Berg, S.,Weigelt, J.,Holmberg-Schiavone, L.,Structural Genomics Consortium (SGC) (deposition date: 2007-05-02, release date: 2007-05-15, Last modification date: 2015-04-22)
Primary citation	Karlberg, T.,Klepsch, M.,Thorsell, A.G.,Andersson, C.D.,Linusson, A.,Schuler, H. Structural Basis for Lack of ADP-ribosyltransferase Activity in Poly(ADP-ribose) Polymerase-13/Zinc Finger Antiviral Protein. J.Biol.Chem., 290:7336-7344, 2015 Cited by PubMed: 25635049 DOI: 10.1074/jbc.M114.630160 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation