2PQC

CP4 EPSPS liganded with (R)-phosphonate tetrahedral reaction intermediate analog

2PQC の概要

• エントリーDOI: 10.2210/pdb2pqc/pdb
• 関連するPDBエントリー: 2GG4 2GG6 2GGA 2PQ9 2PQB 2PQD
• 分子名称: 3-phosphoshikimate 1-carboxyvinyltransferase, [3R-[3A,4A,5B(R*)]]-5-(1-CARBOXY-1-PHOSPHONOETHOXY)-4-HYDROXY-3-(PHOSPHONOOXY)-1-CYCLOHEXENE-1-CARBOXYLIC ACID (3 entities in total)
• 機能のキーワード: inside-out alpha/beta barrel, transferase
• 由来する生物種: Agrobacterium sp.
• 細胞内の位置: Cytoplasm (Probable): Q9R4E4
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 47071.44

構造登録者

Healy-Fried, M.L.,Funke, T.,Han, H.,Schonbrunn, E. (登録日: 2007-05-01, 公開日: 2008-03-11, 最終更新日: 2023-08-30)

• 主引用文献: Funke, T.,Healy-Fried, M.L.,Han, H.,Alberg, D.G.,Bartlett, P.A.,Schonbrunn, E.; Differential inhibition of class I and class II 5-enolpyruvylshikimate-3-phosphate synthases by tetrahedral reaction intermediate analogues.; Biochemistry, 46:13344-13351, 2007; PubMed: 17958399; DOI: 10.1021/bi701095u

実験手法

X-RAY DIFFRACTION (1.6 Å)