2PPZ

NMR solution Structure of the Villin Headpiece Mutant G34L

Summary for 2PPZ

Entry DOI	10.2210/pdb2ppz/pdb
NMR Information	BMRB: 15245
Descriptor	Villin-1 (1 entity in total)
Functional Keywords	small stable core, alpha helical, thermostable, in silico sequence optimization, structural protein
Biological source	Gallus gallus (chicken)
Cellular location	Cytoplasm, cytoskeleton: P02640
Total number of polymer chains	1
Total formula weight	4252.01
Authors	Gronwald, W.,Hohm, T.,Hoffmann, D. (deposition date: 2007-05-01, release date: 2007-05-29, Last modification date: 2024-05-22)
Primary citation	Gronwald, W.,Hohm, T.,Hoffmann, D. Evolutionary Pareto-optimization of stably folding peptides Bmc Bioinformatics, 9:109-109, 2008 Cited by PubMed Abstract: As a rule, peptides are more flexible and unstructured than proteins with their substantial stabilizing hydrophobic cores. Nevertheless, a few stably folding peptides have been discovered. This raises the question whether there may be more such peptides that are unknown as yet. These molecules could be helpful in basic research and medicine. PubMed: 18284690 DOI: 10.1186/1471-2105-9-109 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation