2POT

tRNA guanine transglycosylase (TGT) E235Q mutant in complex with guanine

Summary for 2POT

• Entry DOI: 10.2210/pdb2pot/pdb
• Related: 1P0B
• Descriptor: Queuine tRNA-ribosyltransferase, ZINC ION, GUANINE, ... (5 entities in total)
• Functional Keywords: tgt, e235q mutant, guanine, transferase
• Biological source: Zymomonas mobilis
• Total number of polymer chains: 1
• Total formula weight: 43785.91

Authors

Tidten, N.,Heine, A.,Reuter, K.,Klebe, G. (deposition date: 2007-04-27, release date: 2007-10-30, Last modification date: 2023-08-30)

• Primary citation: Tidten, N.,Stengl, B.,Heine, A.,Garcia, G.A.,Klebe, G.,Reuter, K.; Glutamate versus Glutamine Exchange Swaps Substrate Selectivity in tRNA-Guanine Transglycosylase: Insight into the Regulation of Substrate Selectivity by Kinetic and Crystallographic Studies.; J.Mol.Biol., 374:764-776, 2007; PubMed: 17949745; DOI: 10.1016/j.jmb.2007.09.062

Experimental method

X-RAY DIFFRACTION (1.8 Å)