2PNL

Crystal structure of VP4 protease from infectious pancreatic necrosis virus (IPNV) in space group P1

2PNL の概要

• エントリーDOI: 10.2210/pdb2pnl/pdb
• 関連するPDBエントリー: 2GEF 2PNM
• 分子名称: Protease VP4, GUANIDINE (3 entities in total)
• 機能のキーワード: acyl-enzyme, protease, ser/lys dyad, viral protease, substrate complex, product complex, hydrolase
• 由来する生物種: Infectious pancreatic necrosis virus
• 細胞内の位置: Capsid protein VP2: Virion (Potential). Capsid protein VP3: Virion (Potential). Structural peptide 1: Virion (Potential). Structural peptide 2: Virion (Potential). Structural peptide 3: Virion (Potential): Q703G9
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 218566.01

構造登録者

Paetzel, M.,Lee, J.,Feldman, A.R.,Delmas, B. (登録日: 2007-04-24, 公開日: 2007-06-05, 最終更新日: 2021-10-20)

• 主引用文献: Lee, J.,Feldman, A.R.,Delmas, B.,Paetzel, M.; Crystal structure of the VP4 protease from infectious pancreatic necrosis virus reveals the acyl-enzyme complex for an intermolecular self-cleavage reaction.; J.Biol.Chem., 282:24928-24937, 2007; PubMed: 17553791; DOI: 10.1074/jbc.M701551200

実験手法

X-RAY DIFFRACTION (2.21 Å)