2PMO
Crystal structure of PfPK7 in complex with hymenialdisine
Summary for 2PMO
Entry DOI | 10.2210/pdb2pmo/pdb |
Descriptor | Ser/Thr protein kinase, 4-(5-AMINO-4-OXO-4H-PYRAZOL-3-YL)-2-BROMO-4,5,6,7-TETRAHYDRO-3AH-PYRROLO[2,3-C]AZEPIN-8-ONE (3 entities in total) |
Functional Keywords | ser/thr protein kinase; plasmodium falciparum; transferase; phosphorylation, transferase |
Biological source | Plasmodium falciparum (malaria parasite P. falciparum) |
Total number of polymer chains | 1 |
Total formula weight | 41758.73 |
Authors | Merckx, A.,Echalier, A.,Noble, M.,Endicott, J. (deposition date: 2007-04-23, release date: 2008-01-22, Last modification date: 2023-08-30) |
Primary citation | Merckx, A.,Echalier, A.,Langford, K.,Sicard, A.,Langsley, G.,Joore, J.,Doerig, C.,Noble, M.,Endicott, J. Structures of P. falciparum protein kinase 7 identify an activation motif and leads for inhibitor design. Structure, 16:228-238, 2008 Cited by PubMed: 18275814DOI: 10.1016/j.str.2007.11.014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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