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2PM4

Human alpha-defensin 1 (multiple Arg->Lys mutant)

Summary for 2PM4
Entry DOI10.2210/pdb2pm4/pdb
Related1DFN 1ZMH 1ZMI 1ZMK
DescriptorNeutrophil defensin 1 (HNP-1) (HP-1) (HP1) (Defensin, alpha 1) (2 entities in total)
Functional Keywordsantimicrobial, defensin, mutant, antimicrobial protein
Biological sourceHomo sapiens (human)
Cellular locationSecreted: P59665
Total number of polymer chains2
Total formula weight6824.16
Authors
Lubkowski, J.,Pazgier, M.,Lu, W. (deposition date: 2007-04-20, release date: 2007-05-29, Last modification date: 2023-08-30)
Primary citationZou, G.,de Leeuw, E.,Li, C.,Pazgier, M.,Li, C.,Zeng, P.,Lu, W.Y.,Lubkowski, J.,Lu, W.
Toward understanding the cationicity of defensins. Arg and Lys versus their noncoded analogs.
J.Biol.Chem., 282:19653-19665, 2007
Cited by
PubMed: 17452329
DOI: 10.1074/jbc.M611003200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.95 Å)
Structure validation

222036

건을2024-07-03부터공개중

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