2PM4

Human alpha-defensin 1 (multiple Arg->Lys mutant)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Neutrophil defensin 1 (HNP-1) (HP-1) (HP1) (Defensin, alpha 1)	polymer	30	3412.1	2	UniProt (P59665) Pfam (PF00323) UniProt (by SIFTS) (P59666)	Homo sapiens (human)
2	C, D (A, B)	water	water		18.0	90	Chemie (HOH)

Sequence modifications

A, B: 1 - 30 (UniProt: P59665)

PDB	External Database	Details
Asp 1	Ala 65	conflict
Lys 14	Arg 78	engineered mutation
Lys 15	Arg 79	engineered mutation
Lys 24	Arg 88	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	6824.2
All*	Total formula weight	6824.2

*Water molecules are not included.