2PKN

Crystal structure of M tuberculosis Adenosine Kinase complexed with AMP-PCP (non-hydrolyzable ATP analog)

Summary for 2PKN

• Entry DOI: 10.2210/pdb2pkn/pdb
• Related: 1BX4 1RKA 1RKD 2PKF 2PKK 2PKM
• Descriptor: Adenosine kinase, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER (3 entities in total)
• Functional Keywords: mycobacterium tuberculosis, adenosine kinase, transferase, structural genomics, tb structural genomics consortium, tbsgc, psi-2, protein structure initiative
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 1
• Total formula weight: 36188.37

Authors

Reddy, M.C.M.,Palaninathan, S.K.,Shetty, N.D.,Owen, J.L.,Watson, M.D.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2007-04-18, release date: 2007-06-19, Last modification date: 2024-04-03)

• Primary citation: Reddy, M.C.M.,Palaninathan, S.K.,Shetty, N.D.,Owen, J.L.,Watson, M.D.,Sacchettini, J.C.; High resolution crystal structures of Mycobacterium tuberculosis adenosine kinase: insights into the mechanism and specificity of this novel prokaryotic enzyme; J.Biol.Chem., 282:27334-27342, 2007; PubMed: 17597075; DOI: 10.1074/jbc.M703290200

Experimental method

X-RAY DIFFRACTION (1.9 Å)