2PIE
Crystal structure of the FHA domain of RNF8 in complex with its optimal phosphopeptide
Summary for 2PIE
Entry DOI | 10.2210/pdb2pie/pdb |
Related | 2CSW |
Descriptor | E3 ubiquitin-protein ligase RNF8, phosphopeptide (3 entities in total) |
Functional Keywords | fha domain, phosphopeptide, complex, ligase, signaling protein |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus : O76064 |
Total number of polymer chains | 2 |
Total formula weight | 16812.03 |
Authors | Grant, R.A.,Yaffe, M.B. (deposition date: 2007-04-13, release date: 2007-12-11, Last modification date: 2023-08-30) |
Primary citation | Huen, M.S.,Grant, R.,Manke, I.,Minn, K.,Yu, X.,Yaffe, M.B.,Chen, J. RNF8 Transduces the DNA-Damage Signal via Histone Ubiquitylation and Checkpoint Protein Assembly. Cell(Cambridge,Mass.), 131:901-914, 2007 Cited by PubMed: 18001825DOI: 10.1016/j.cell.2007.09.041 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.35 Å) |
Structure validation
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