2PI6

Crystal structure of the sheep signalling glycoprotein (SPS-40) complex with 2-methyl-2-4-pentanediol at 1.65A resolution reveals specific binding characteristics of SPS-40

Summary for 2PI6

• Entry DOI: 10.2210/pdb2pi6/pdb
• Related: 1ZL1 2DPE
• Descriptor: Chitinase-3-like protein 1, alpha-D-mannopyranose-(1-4)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (5 entities in total)
• Functional Keywords: complex, signaling protein
• Biological source: Ovis aries (sheep)
• Total number of polymer chains: 1
• Total formula weight: 42042.40

Authors

Sharma, P.,Singh, N.,Sharma, S.,Kaur, P.,Betzel, C.,Singh, T.P. (deposition date: 2007-04-13, release date: 2007-05-01, Last modification date: 2023-10-25)

• Primary citation: Sharma, P.,Singh, N.,Sinha, M.,Sharma, S.,Perbandt, M.,Betzel, C.,Kaur, P.,Srinivasan, A.,Singh, T.P.; Tryptophan as a three-way switch in regulating the function of the secretory signalling glycoprotein (SPS-40) from mammary glands: structure of SPS-40 complexed with 2-methylpentane-2,4-diol at 1.6 A resolution.; Acta Crystallogr.,Sect.D, 65:375-378, 2009; PubMed: 19307719; DOI: 10.1107/S0907444909002327

Experimental method

X-RAY DIFFRACTION (1.65 Å)