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2PGL

Catalysis associated conformational changes revealed by human CD38 complexed with a non-hydrolyzable substrate analog

Summary for 2PGL
Entry DOI10.2210/pdb2pgl/pdb
Related2PGJ
DescriptorADP-ribosyl cyclase 1, N1-CYCLIC INOSINE 5'-DIPHOSPHORIBOSE (3 entities in total)
Functional Keywordshuman cd38 e226q mutant bound with n1-cidpr, the catalytic pocket, conformational changes of the active site, substrate analog binding, hydrolase
Biological sourceHomo sapiens (human)
Cellular locationMembrane; Single-pass type II membrane protein: P28907
Total number of polymer chains2
Total formula weight61301.10
Authors
Liu, Q.,Kriksunov, I.A.,Moreau, C.,Graeff, R.,Potter, B.V.L.,Lee, H.C.,Hao, Q. (deposition date: 2007-04-09, release date: 2007-04-24, Last modification date: 2023-08-30)
Primary citationLiu, Q.,Kriksunov, I.A.,Moreau, C.,Graeff, R.,Potter, B.V.,Lee, H.C.,Hao, Q.
Catalysis-associated Conformational Changes Revealed by Human CD38 Complexed with a Non-hydrolyzable Substrate Analog
J.Biol.Chem., 282:24825-24832, 2007
Cited by
PubMed: 17591784
DOI: 10.1074/jbc.M701653200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.76 Å)
Structure validation

217705

數據於2024-03-27公開中

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