2PGL
Catalysis associated conformational changes revealed by human CD38 complexed with a non-hydrolyzable substrate analog
Summary for 2PGL
Entry DOI | 10.2210/pdb2pgl/pdb |
Related | 2PGJ |
Descriptor | ADP-ribosyl cyclase 1, N1-CYCLIC INOSINE 5'-DIPHOSPHORIBOSE (3 entities in total) |
Functional Keywords | human cd38 e226q mutant bound with n1-cidpr, the catalytic pocket, conformational changes of the active site, substrate analog binding, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Membrane; Single-pass type II membrane protein: P28907 |
Total number of polymer chains | 2 |
Total formula weight | 61301.10 |
Authors | Liu, Q.,Kriksunov, I.A.,Moreau, C.,Graeff, R.,Potter, B.V.L.,Lee, H.C.,Hao, Q. (deposition date: 2007-04-09, release date: 2007-04-24, Last modification date: 2023-08-30) |
Primary citation | Liu, Q.,Kriksunov, I.A.,Moreau, C.,Graeff, R.,Potter, B.V.,Lee, H.C.,Hao, Q. Catalysis-associated Conformational Changes Revealed by Human CD38 Complexed with a Non-hydrolyzable Substrate Analog J.Biol.Chem., 282:24825-24832, 2007 Cited by PubMed: 17591784DOI: 10.1074/jbc.M701653200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.76 Å) |
Structure validation
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