2PEY

Crystal structure of deletion mutant of APS-kinase domain of human PAPS-synthetase 1

Summary for 2PEY

Entry DOI	10.2210/pdb2pey/pdb
Related	2pez
Descriptor	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 (PAPS synthetase 1) (PAPSS 1) (Sulfurylase kinase 1) (SK1) (SK 1), ADENOSINE-5'-PHOSPHOSULFATE, 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
Functional Keywords	protein-nucleic acid complex, nmp-kinase fold, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	40998.63
Authors	Sekulic, N.,Lavie, A. (deposition date: 2007-04-03, release date: 2007-05-29, Last modification date: 2023-08-30)
Primary citation	Sekulic, N.,Konrad, M.,Lavie, A. Structural mechanism for substrate inhibition of the adenosine 5'-phosphosulfate kinase domain of human 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 and its ramifications for enzyme regulation. J.Biol.Chem., 282:22112-22121, 2007 Cited by PubMed: 17540769 DOI: 10.1074/jbc.M701713200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.88 Å)

Structure validation