2PEH
Crystal structure of the UHM domain of human SPF45 in complex with SF3b155-ULM5
Summary for 2PEH
Entry DOI | 10.2210/pdb2peh/pdb |
Related | 2PE8 |
Descriptor | Splicing factor 45, Splicing factor 3B subunit 1 (3 entities in total) |
Functional Keywords | rrm, uhm, protein binding |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q96I25 Nucleus speckle: O75533 |
Total number of polymer chains | 4 |
Total formula weight | 25993.90 |
Authors | Corsini, L.,Basquin, J.,Hothorn, M.,Sattler, M. (deposition date: 2007-04-03, release date: 2007-06-26, Last modification date: 2023-08-30) |
Primary citation | Corsini, L.,Bonna, S.,Basquin, J.,Hothorn, M.,Scheffzek, K.,Valcarcel, J.,Sattler, M. U2AF-homology motif interactions are required for alternative splicing regulation by SPF45. Nat.Struct.Mol.Biol., 14:620-629, 2007 Cited by PubMed: 17589525DOI: 10.1038/nsmb1260 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.11 Å) |
Structure validation
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