2PA5

Crystal structure of human protein tyrosine phosphatase PTPN9

Summary for 2PA5

• Entry DOI: 10.2210/pdb2pa5/pdb
• Related: 2HNQ
• Descriptor: Tyrosine-protein phosphatase non-receptor type 9, CHLORIDE ION, THIOCYANATE ION, ... (5 entities in total)
• Functional Keywords: protein tyrosine phosphatase, meg2, ptpn9, structural genomics, structural genomics consortium, sgc, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm : P43378
• Total number of polymer chains: 2
• Total formula weight: 72968.34

Authors

Ugochukwu, E.,Barr, A.,Pike, A.C.W.,Savitsky, P.,Papagrigoriou, E.,Turnbull, A.,Uppenberg, J.,Bunkoczi, G.,Salah, E.,Das, S.,von Delft, F.,Sundstrom, M.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2007-03-27, release date: 2007-05-15, Last modification date: 2023-08-30)

• Primary citation: Barr, A.J.,Ugochukwu, E.,Lee, W.H.,King, O.N.,Filippakopoulos, P.,Alfano, I.,Savitsky, P.,Burgess-Brown, N.A.,Muller, S.,Knapp, S.; Large-scale structural analysis of the classical human protein tyrosine phosphatome.; Cell(Cambridge,Mass.), 136:352-363, 2009; PubMed: 19167335; DOI: 10.1016/j.cell.2008.11.038

Experimental method

X-RAY DIFFRACTION (1.6 Å)