2P6B
Crystal Structure of Human Calcineurin in Complex with PVIVIT Peptide
Summary for 2P6B
Entry DOI | 10.2210/pdb2p6b/pdb |
Descriptor | PVIVIT 14-mer Peptide, Calmodulin-dependent calcineurin A subunit alpha isoform, Calcineurin subunit B isoform 1, ... (8 entities in total) |
Functional Keywords | beta-sheet augmentation; protein-peptide complex, hydrolase-hydrolase regulator complex, hydrolase/hydrolase regulator |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 125727.47 |
Authors | Li, H.,Zhang, L.,Rao, A.,Harrison, S.C.,Hogan, P.G. (deposition date: 2007-03-16, release date: 2007-06-05, Last modification date: 2023-08-30) |
Primary citation | Li, H.,Zhang, L.,Rao, A.,Harrison, S.C.,Hogan, P.G. Structure of calcineurin in complex with PVIVIT peptide: Portrait of a low-affinity signalling interaction J.Mol.Biol., 369:1296-1306, 2007 Cited by PubMed: 17498738DOI: 10.1016/j.jmb.2007.04.032 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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