2P6B

Crystal Structure of Human Calcineurin in Complex with PVIVIT Peptide

2P6B の概要

分子名称PVIVIT 14-mer Peptide, Calmodulin-dependent calcineurin A subunit alpha isoform, Calcineurin subunit B isoform 1, ... (8 entities in total)
機能のキーワードbeta-sheet augmentation; protein-peptide complex, hydrolase-hydrolase regulator complex, hydrolase/hydrolase regulator
由来する生物種Homo sapiens (human)
詳細
細胞内の位置Cell membrane  Q08209
Cytoplasm, cytosol  P63098
ポリマー鎖数5
分子量合計125727.47
構造登録者
Li, H.,Zhang, L.,Rao, A.,Harrison, S.C.,Hogan, P.G. (登録日: 2007-03-16, 公開日: 2007-06-05, 最終更新日: 2017-10-18)
主引用文献
Li, H.,Zhang, L.,Rao, A.,Harrison, S.C.,Hogan, P.G.
Structure of calcineurin in complex with PVIVIT peptide: Portrait of a low-affinity signalling interaction
J.Mol.Biol., 369:1296-1306, 2007
PubMed: 17498738 (主引用文献が同じPDBエントリー)
DOI: 10.1016/j.jmb.2007.04.032
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2.3 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.247120.5%1.6%5.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード