2P5N

Crystal structure of mouse 17-alpha hydroxysteroid dehydrogenase in complex with coenzyme NADPH

2P5N の概要

• エントリーDOI: 10.2210/pdb2p5n/pdb
• 分子名称: Aldo-keto reductase family 1, member C21, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (4 entities in total)
• 機能のキーワード: aldo-keto reductase, hydroxysteroid dehydrogenase, binary complex, tim barrel, oxidoreductase
• 由来する生物種: Mus musculus (house mouse)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 75576.35

構造登録者

El-Kabbani, O.,Dhagat, U. (登録日: 2007-03-15, 公開日: 2007-10-09, 最終更新日: 2023-10-25)

• 主引用文献: Dhagat, U.,Carbone, V.,Chung, R.P.,Schulze-Briese, C.,Endo, S.,Hara, A.,El-Kabbani, O.; Structure of 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21) holoenzyme from an orthorhombic crystal form: an insight into the bifunctionality of the enzyme.; Acta Crystallogr.,Sect.F, 63:825-830, 2007; PubMed: 17909281; DOI: 10.1107/S1744309107040985

実験手法

X-RAY DIFFRACTION (1.8 Å)