2P0C
Catalytic Domain of the Proto-oncogene Tyrosine-protein Kinase MER
2P0C の概要
エントリーDOI | 10.2210/pdb2p0c/pdb |
分子名称 | Proto-oncogene tyrosine-protein kinase MER, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (5 entities in total) |
機能のキーワード | atp-binding, disease mutation, glycoprotein, kinase, nucleotide-binding, phosphorylation, proto-oncogene, receptor, retinitis pigmentosa, sensory transduction, transferase, tyrosine-protein kinase, vision, structural genomics, structural genomics consortium, sgc |
由来する生物種 | Homo sapiens (human) |
細胞内の位置 | Membrane; Single-pass type I membrane protein (By similarity): Q12866 |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 72942.31 |
構造登録者 | Walker, J.R.,Huang, X.,Finerty Jr., P.J.,Weigelt, J.,Sundstrom, M.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (登録日: 2007-02-28, 公開日: 2007-05-08, 最終更新日: 2023-08-30) |
主引用文献 | Huang, X.,Finerty, P.,Walker, J.R.,Butler-Cole, C.,Vedadi, M.,Schapira, M.,Parker, S.A.,Turk, B.E.,Thompson, D.A.,Dhe-Paganon, S. Structural insights into the inhibited states of the Mer receptor tyrosine kinase. J.Struct.Biol., 165:88-96, 2009 Cited by PubMed: 19028587DOI: 10.1016/j.jsb.2008.10.003 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.4 Å) |
構造検証レポート
検証レポート(詳細版)をダウンロード