2OUI

D275P mutant of alcohol dehydrogenase from protozoa Entamoeba histolytica

Summary for 2OUI

• Entry DOI: 10.2210/pdb2oui/pdb
• Related: 1Y9A
• Descriptor: NADP-dependent alcohol dehydrogenase, ZINC ION, NITRATE ION, ... (10 entities in total)
• Functional Keywords: tetramer, metal-binding, nadp, oxidoreductase, p275d mutation, cacodylate ion, thermosatbility
• Biological source: Entamoeba histolytica
• Cellular location: Cytoplasm: P35630
• Total number of polymer chains: 4
• Total formula weight: 157099.26

Authors

Frolow, F.,Shimon, L.,Burstein, Y.,Goihberg, E.,Peretz, M.,Dym, O. (deposition date: 2007-02-11, release date: 2008-02-12, Last modification date: 2023-10-25)

• Primary citation: Goihberg, E.,Dym, O.,Tel-Or, S.,Shimon, L.,Frolow, F.,Peretz, M.,Burstein, Y.; Thermal stabilization of the protozoan Entamoeba histolytica alcohol dehydrogenase by a single proline substitution.; Proteins, 72:711-719, 2008; PubMed: 18260103; DOI: 10.1002/prot.21946

Experimental method

X-RAY DIFFRACTION (1.77 Å)