2ORQ

Murine Inducible Nitric Oxide Synthase Oxygenase Domain (DELTA 114) 4-(imidazol-1-yl)phenol and piperonylamine Complex

Summary for 2ORQ

Entry DOI	10.2210/pdb2orq/pdb
Related	1DD7 1NOC 1NOD 1NOS 1NSI 2NOS 2ORO 2ORP 2ORR 2ORS 2ORT
Descriptor	Nitric oxide synthase, inducible, PROTOPORPHYRIN IX CONTAINING FE, 4-(1H-IMIDAZOL-1-YL)PHENOL, ... (5 entities in total)
Functional Keywords	nitric oxide, l-arginine monooxygenase, heme, dimerization, inhibitor, nos, oxidoreductase
Biological source	Mus musculus (house mouse)
Total number of polymer chains	1
Total formula weight	46198.20
Authors	Adler, M.,Whitlow, M. (deposition date: 2007-02-04, release date: 2007-04-17, Last modification date: 2024-02-21)
Primary citation	Davey, D.D.,Adler, M.,Arnaia, D.,Eagen, K.,Erickson, S.,Guilford, W.,Kenrick, M.,Morrissey, M.M.,Ohimeyer, M.,Pan, G.,Paradkar, V.M.,Parkinson, J.,Polokoff, M.,Salonz, K.,Santos, C.,Subramanyam, B.,Vergona, R.,Wei, R.G.,Whitlow, M.,Ye, B.,Zhao, Z.S.,Devlin, J.J.,Phillips, G. Design, Synthesis, and Activity of 2-Imidazol-1-ylpyrimidine Derived Inducible Nitric Oxide Synthase Dimerization Inhibitors J.Med.Chem., 50:1146-1157, 2007 Cited by PubMed: 17315988 DOI: 10.1021/jm061319i PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation