2ORK

crystal structure of the trimeric neck and carbohydrate recognition domain of human surfactant protein D in complex with inositol-1-phosphate

Summary for 2ORK

• Entry DOI: 10.2210/pdb2ork/pdb
• Related: 2GGU 2ORJ
• Descriptor: Pulmonary surfactant-associated protein D, CALCIUM ION, D-MYO-INOSITOL-1-PHOSPHATE, ... (4 entities in total)
• Functional Keywords: surfactant protein, carbohydrate recognition domain, trimeric, sugar binding protein
• Biological source: Homo sapiens (human)
• Cellular location: Secreted, extracellular space, extracellular matrix: P35247
• Total number of polymer chains: 3
• Total formula weight: 52693.57

Authors

Head, J.F. (deposition date: 2007-02-02, release date: 2007-05-08, Last modification date: 2023-08-30)

• Primary citation: Crouch, E.,McDonald, B.,Smith, K.,Roberts, M.,Mealy, T.,Seaton, B.,Head, J.; Critical Role of Arg/Lys343 in the Species-Dependent Recognition of Phosphatidylinositol by Pulmonary Surfactant Protein D.; Biochemistry, 46:5160-5169, 2007; PubMed: 17417879; DOI: 10.1021/bi700037x

Experimental method

X-RAY DIFFRACTION (1.89 Å)