2OR9
The structure of the anti-c-myc antibody 9E10 Fab fragment/epitope peptide complex reveals a novel binding mode dominated by the heavy chain hypervariable loops
Summary for 2OR9
Entry DOI | 10.2210/pdb2or9/pdb |
Related | 2ORB |
Descriptor | Monoclonal anti-c-myc antibody 9E10, synthetic epitope peptide of 9E10, ... (4 entities in total) |
Functional Keywords | antigen-antibody complex, antigen recognition, myc-tag, long cdr h3, immune system |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 5 |
Total formula weight | 99121.09 |
Authors | Krauss, N.,Scheerer, P.,Hoehne, W. (deposition date: 2007-02-02, release date: 2008-02-12, Last modification date: 2023-08-30) |
Primary citation | Krauss, N.,Wessner, H.,Welfle, K.,Welfle, H.,Scholz, C.,Seifert, M.,Zubow, K.,Ay, J.,Hahn, M.,Scheerer, P.,Skerra, A.,Hohne, W. The structure of the anti-c-myc antibody 9E10 Fab fragment/epitope peptide complex reveals a novel binding mode dominated by the heavy chain hypervariable loops. Proteins, 73:552-565, 2008 Cited by PubMed: 18473392DOI: 10.1002/prot.22080 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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