2OR9

The structure of the anti-c-myc antibody 9E10 Fab fragment/epitope peptide complex reveals a novel binding mode dominated by the heavy chain hypervariable loops

Summary for 2OR9

Related2ORB
DescriptorMonoclonal anti-c-myc antibody 9E10, synthetic epitope peptide of 9E10, ... (4 entities in total)
Functional Keywordsantigen-antibody complex, antigen recognition, myc-tag, long cdr h3, immune system
Biological sourceMus musculus (house mouse)
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Total number of polymer chains5
Total molecular weight99121.09
Authors
Krauss, N.,Scheerer, P.,Hoehne, W. (deposition date: 2007-02-02, release date: 2008-02-12, Last modification date: 2011-07-13)
Primary citation
Krauss, N.,Wessner, H.,Welfle, K.,Welfle, H.,Scholz, C.,Seifert, M.,Zubow, K.,Ay, J.,Hahn, M.,Scheerer, P.,Skerra, A.,Hohne, W.
The structure of the anti-c-myc antibody 9E10 Fab fragment/epitope peptide complex reveals a novel binding mode dominated by the heavy chain hypervariable loops.
Proteins, 73:552-565, 2008
PubMed: 18473392 (PDB entries with the same primary citation)
DOI: 10.1002/prot.22080
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.7 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.30926 0.7% 4.2% 4.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171916
PDB entries from 2020-12-02