2OPZ

AVPF bound to BIR3-XIAP

Summary for 2OPZ

• Entry DOI: 10.2210/pdb2opz/pdb
• Related: 1G3F 2OPY
• Descriptor: Baculoviral IAP repeat-containing protein 4, AVPF (Smac homologue, N-terminal tetrapeptide), ZINC ION (3 entities in total)
• Functional Keywords: tetrapeptide, bir3 domain of xiap, apoptosis inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 8
• Total formula weight: 52407.92

Authors

Wist, A.D. (deposition date: 2007-01-30, release date: 2007-02-20, Last modification date: 2023-12-27)

• Primary citation: Wist, A.D.,Gu, L.,Riedl, S.J.,Shi, Y.,McLendon, G.L.; Structure-activity based study of the Smac-binding pocket within the BIR3 domain of XIAP.; Bioorg.Med.Chem., 15:2935-2943, 2007; PubMed: 17336535; DOI: 10.1016/j.bmc.2007.02.010

Experimental method

X-RAY DIFFRACTION (3 Å)