2OE5

1.5 A X-ray crystal structure of Apramycin complex with RNA fragment GGCGUCGCUAGUACCG/GGUACUAAAAGUCGCCC containing the human ribosomal decoding A site: RNA construct with 3'-overhang

Summary for 2OE5

• Entry DOI: 10.2210/pdb2oe5/pdb
• Related: 2OE6 2OE8
• Descriptor: RNA (5'-R(*GP*GP*CP*GP*UP*CP*GP*CP*UP*AP*GP*UP*AP*CP*CP*G)-3'), RNA (5'-R(*GP*GP*UP*AP*CP*UP*AP*AP*AP*AP*GP*UP*CP*GP*CP*CP*C)-3'), SULFATE ION, ... (6 entities in total)
• Functional Keywords: aminoglycoside antibiotics, apramycin, ribosomal decoding site, a site, homo sapiens, rna duplex, rna
• Total number of polymer chains: 2
• Total formula weight: 11239.65

Authors

Hermann, T.,Tereshko, V.,Skripkin, E.,Patel, D.J. (deposition date: 2006-12-28, release date: 2007-02-13, Last modification date: 2024-04-03)

• Primary citation: Hermann, T.,Tereshko, V.,Skripkin, E.,Patel, D.J.; Apramycin recognition by the human ribosomal decoding site.; Blood Cells Mol.Dis., 38:193-198, 2007; PubMed: 17258916; DOI: 10.1016/j.bcmd.2006.11.006

Experimental method

X-RAY DIFFRACTION (1.51 Å)