2ODE

Crystal structure of the heterodimeric complex of human RGS8 and activated Gi alpha 3

2ODE の概要

分子名称Guanine nucleotide-binding protein G(k) subunit alpha, Regulator of G-protein signaling 8, TETRAFLUOROALUMINATE ION, ... (6 entities in total)
機能のキーワードg protein signalling, rgs, heterotrimeric g protein, signalling complex, structural genomics, structural genomics consortium, sgc, signaling protein
由来する生物種Homo sapiens (human)
細胞内の位置Cytoplasm P08754
ポリマー鎖数4
分子量合計114703.9
構造登録者
主引用文献
Soundararajan, M.,Willard, F.S.,Kimple, A.J.,Turnbull, A.P.,Ball, L.J.,Schoch, G.A.,Gileadi, C.,Fedorov, O.Y.,Dowler, E.F.,Higman, V.A.,Hutsell, S.Q.,Sundstrom, M.,Doyle, D.A.,Siderovski, D.P.
Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105:6457-6462, 2008
PubMed: 18434541 (主引用文献が同じPDBエントリー)
DOI: 10.1073/pnas.0801508105
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (1.9 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.213300.8%6.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード