2OAT
ORNITHINE AMINOTRANSFERASE COMPLEXED WITH 5-FLUOROMETHYLORNITHINE
Summary for 2OAT
| Entry DOI | 10.2210/pdb2oat/pdb |
| Descriptor | ORNITHINE AMINOTRANSFERASE, 1-AMINO-7-(2-METHYL-3-OXIDO-5-((PHOSPHONOXY)METHYL)-4-PYRIDOXAL-5-OXO-6-HEPTENATE (3 entities in total) |
| Functional Keywords | aminotransferase, 5-fluoromethylornithine, plp-dependent enzyme, pyridoxal phosphate |
| Biological source | Homo sapiens (human) |
| Cellular location | Mitochondrion matrix: P04181 |
| Total number of polymer chains | 3 |
| Total formula weight | 146903.85 |
| Authors | Storici, P.,Schirmer, T. (deposition date: 1998-05-07, release date: 1998-12-09, Last modification date: 2023-08-09) |
| Primary citation | Storici, P.,Capitani, G.,Muller, R.,Schirmer, T.,Jansonius, J.N. Crystal structure of human ornithine aminotransferase complexed with the highly specific and potent inhibitor 5-fluoromethylornithine. J.Mol.Biol., 285:297-309, 1999 Cited by PubMed: 9878407DOI: 10.1006/jmbi.1998.2289 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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